Mast cells in the labial salivary glands of patients with Sjogren's syndrome: a histochemical, immunohistochemical, and electron microscopical study.
نویسندگان
چکیده
منابع مشابه
Characterisation of follicular dendritic cells in labial salivary glands of patients with primary Sjögren syndrome: comparison with tonsillar lymphoid follicles.
OBJECTIVE To localise and characterise follicular dendritic cells (FDC) present in autoimmune lesions of primary Sjögren syndrome. METHODS Cryostat sections of labial salivary glands from 15 patients with primary Sjögren syndrome were examined by an indirect immunoperoxidase technique and monoclonal antibodies to a panel of dendritic cell markers. Tonsils from two controls were also examined ...
متن کاملImmunoglobulin-containing cells in normal human labial salivary glands.
The distribution of immunoglobulin-containing cells within 8 normal human labial salivary glands was studied using an immunoperoxidase technique. Cell counts revealed that IgA-containing cells pre-dominated in all specimens and that the mean percentage class ratios for IgG:IgA:IgM:IgD cells were 4:92:3:1. IgE cells were rare and only detected in one gland. The density of IgA cells (191 cells/mm...
متن کاملCommon T cell receptor clonotype in lacrimal glands and labial salivary glands from patients with Sjögren's syndrome.
Sjogren's syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration into lacrimal and salivary glands leading to symptomatic dry eyes and mouth. Immunohistological studies have clarified that the majority of infiltrating lymphocytes around the lacrimal glands and labial salivary glands are CD4 positive alphabeta T cells. To analyze the pathogenesis of T cells infiltrating...
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15 صفحه اولSelective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients
The aim of this study was to investigate the initiation and progression of autoimmune damage in the lesions of labial salivary glands (LSGs) from primary Sjögren's syndrome (SS) patients by examining the selective localization of T helper (Th) subsets such as Th1, Th2, Th17 regulatory T cells (T(regs)) and follicular T helper cells (Tfh). The expression of cytokines and transcription factors as...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1990
ISSN: 0003-4967
DOI: 10.1136/ard.49.9.685